Jason Carroll publications

The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells
Thiruchelvam PTR;Lai CF;Hua H;Thomas RS;Hurtado A;Hudson W;Bayly AR;Kyle FJ;Periyasamy M;Photiou A;Spivey AC;Ortlund EA;Whitby RJ;Carroll JS;Coombes RC;Buluwela L;Ali S
Breast Cancer Res Treat 2011; 127 (2):385-396.
PubMed;  DOI: 10.1007/s10549-010-0994-9.

FOXA1 is a key determinant of estrogen receptor function and endocrine response
Hurtado A;Holmes KA;Ross-Innes CS;Schmidt D;Carroll JS
Nat Genet 2011; 43 (1):27-33.
UKPubMed (open access);  PubMed;  DOI: 10.1038/ng.730.

Estrogen receptor-positive breast cancer: a multidisciplinary challenge.
Zwart W;Theodorou V;Carroll JS
Wiley Interdiscip Rev Syst Biol Med 2010; 3 (2 ):216-230.
PubMed;  DOI: 10.1002/wsbm.109.

High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53-NF-kappaB-complex-dependent gene expression in human heart failure.
Choy MK;Movassagh M;Siggens L;Vujic A;Goddard M;Sanchez A;Perkins N;Figg N;Bennett M;Carroll J;Foo R
Genome Med 2010; 2 (6):37.
UKPubMed (open access);  PubMed;  DOI: 10.1186/gm158.

Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications.
Badve S;Collins NR;Bhat-Nakshatri P;Turbin D;Leung S;Thorat M;Dunn SE;Geistlinger TR;Carroll JS;Brown M;Bose S;Teitell MA;Nakshatri H
Am J Pathol 2010; 176 (5):2139-2149.
UKPubMed (open access);  PubMed;  DOI: 10.2353/ajpath.2010.090477.

Growth factor stimulation induces a distinct ER alpha cistrome underlying breast cancer endocrine resistance
Lupien M;Meyer CA;Bailey ST;Eeckhoute J;Cook J;Westerling T;Zhang XY;Carroll JS;Rhodes DR;Liu XS;Brown M
Genes Dev 2010; 24 (19):2219-2227.
DOI: 10.1101/gad.1944810.

Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding
Schmidt D;Wilson MD;Ballester B;Schwalie PC;Brown GD;Marshall A;Kutter C;Watt S;Martinez-Jimenez CP;Mackay S;Talianidis I;Flicek P;Odom DT
Science 2010; 328 (5981):1036-1040.
PubMed;  DOI: 10.1126/science.1186176.

A CTCF-independent role for cohesin in tissue-specific transcription
Schmidt D;Schwalie PC;Ross-Innes CS;Hurtado A;Brown GD;Carroll JS;Flicek P;Odom DT
Genome Res 2010; 20 (5):578-588.
UKPubMed (open access);  PubMed;  DOI: 10.1101/gr.100479.109.

Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer
Ross-Innes CS;Stark R;Holmes KA;Schmidt D;Spyrou C;Russell R;Massie CE;Vowler SL;Eldridge M;Carroll JS
Genes Dev 2010; 24 (2):171-182.
UKPubMed (open access);  PubMed;  DOI: 10.1101/gad.552910.

Defining and targeting transcription factors in cancer.
Redmond AM;Carroll JS
Genome Biol 2009; 10 (7):311.
UKPubMed (open access);  PubMed;  DOI: 10.1186/gb-2009-10-7-311.

Estrogen Regulation of Cyclin E2 Requires Cyclin D1 but Not c-Myc
Caldon CE;Sergio CM;Schutte J;Boersma MN;Sutherland RL;Carroll JS;Musgrove EA
Mol Cell Biol 2009; 29 (17):4623-4639.
UKPubMed (open access);  PubMed;  DOI: 10.1128/MCB.00269-09.

Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
Wang QB;Li W;Zhang Y;Yuan X;Xu KX;Yu JD;Chen Z;Beroukhim R;Wang HY;Lupien M;Wu T;Regan MM;Meyer CA;Carroll JS;Manrai AK;Janne OA;Balk SP;Mehra R;Han B;Chinnaiyan AM;Rubin MA;True L;Fiorentino M;Fiore C;Loda M;Kantoff PW;Liu XS;Brown M
Cell 2009; 138 (2):245-256.
PubMed; 

Interrogating the genome to understand oestrogen-receptor-mediated transcription
Dietz SC;Carroll JS
Expert Rev Mol Med 2008; 10 ():e10.
PubMed;  DOI: 10.1017/S1462399408000653.

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription
Lupien M;Eeckhoute J;Meyer CA;Wang QB;Zhang Y;Li W;Carroll JS;Liu XS;Brown M
Cell 2008; 132 (6):958-970.

xMAN: extreme MApping of OligoNucleotides
Li W;Carroll JS;Brown M;Liu S
BMC Genomics 2008; 9 (Suppl 1):S20.

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival
Krum SA;Miranda-Carboni GA;Hauschka PV;Carroll JS;Lane TF;Freedman LP;Brown M
EMBO J 2008; 27 (3):535-545.

AKT Alters Genome-Wide Estrogen Receptor alpha Binding and Impacts Estrogen Signaling in Breast Cancer
Bhat-Nakshatri P;Wang GH;Appaiah H;Luktuke N;Carroll JS;Geistlinger TR;Brown M;Badve S;Liu YL;Nakshatri H
Mol Cell Biol 2008; 28 (24):7487-7503.

Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen
Hurtado A;Holmes KA;Geistlinger TR;Hutcheson IR;Nicholson RI;Brown M;Jiang J;Howat WJ;Ali S;Carroll JS
Nature 2008; 456 (7222):663-666.
PubMed;  DOI: 10.1038/nature07483.

Unique ER alpha Cistromes Control Cell Type-Specific Gene Regulation
Krum SA;Miranda-Carboni GA;Lupien M;Eeckhoute J;Carroll JS;Brown M
Mol Endocrinol 2008; 22 (11):2393-2406.

Nkx3-1 and LEF-1 function as transcriptional inhibitors of estrogen receptor activity
Holmes KA;Song JS;Liu XLS;Brown M;Carroll JS
Cancer Res 2008; 68 (18):7380-7385.

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets
Johnson DS;Li W;Gordon DB;Bhattacharjee A;Curry B;Ghosh J;Brizuela L;Carroll JS;Brown M;Flicek P;Koch CM;Dunham I;Bieda M;Xu XQ;Farnham PJ;Kapranov P;Nix DA;Gingeras TR;Zhang XM;Holster H;Jiang N;Green RD;Song JS;Mccuine SA;Anton E;Nguyen L;Trinklein ND;Ye Z;Ching K;Hawkins D;Ren B;Scacheri PC;Rozowsky J;Karpikov A;Euskirchen G;Weissman S;Gerstein M;Snyder M;Yang A;Moqtaderi Z;Hirsch H;Shulha HP;Fu YT;Weng ZP;Struhl K;Myers RM;Lieb JD;Liu XS
Genome Res 2008; 18 (3):393-403.

Opinion - Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state
Green KA;Carroll JS
Nat Rev Cancer 2007; 7 (9):713-722.