Simon Tavaré publications

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Cambridge Research Institute
Li Ka Shing Centre
Robinson Way
Cambridge
CB2 0RE
United Kingdom

Primary research papers

The following publications have been supported by Cancer Research UK funding for this researcher.

2011

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
Holland DG;Burleigh A;Git A;Goldgraben MA;Perez-Mancera PA;Chin SF;Hurtado A;Bruna A;Ali HR;Greenwood W;Dunning MJ;Samarajiwa S;Menon S;Rueda OM;Lynch AG;McKinney S;Ellis IO;Eaves CJ;Carroll JS;Curtis C;Aparicio S;Caldas C
EMBO Mol Med 2011; 3 (3 ):167-180.
DOI: 10.1002/emmm.201100122.

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression
Ibrahim AEK;Arends MJ;Silva AL;Wyllie AH;Greger L;Ito Y;Vowler SL;Huang THM;Tavare S;Murrell A;Brenton JD
Gut 2011; 60 (4 ):499-508.
PubMed;  DOI: 10.1136/gut.2010.223602.

BayesPeak-an R package for analysing ChIP-seq data
Cairns J;Spyrou C;Stark R;Smith ML;Lynch AG;Tavare S
Bioinformatics 2011; 27 (5 ):713-714.
UKPubMed (open access)PubMed;  DOI: 10.1093/bioinformatics/btq685.

Systems biology of interferon responses
Hertzog PJ;Forster S;Samarajiwa S
J Interferon Cytokine Res 2011; 31 ():5-11.

2010

BeadDataPackR: A Tool to Facilitate the Sharing of Raw Data from Illumina BeadArray Studies.
Smith ML;Lynch AG
Cancer Inform 2010; 9 ():217-227.
UKPubMed (open access)PubMed; 

CNAseg-a novel framework for identification of copy number changes in cancer from second-generation sequencing data
Ivakhno S;Royce T;Cox AJ;Evers DJ;Cheetham RK;Tavare S
Bioinformatics 2010; 26 (24):3051-3058.
PubMed;  DOI: 10.1093/bioinformatics/btq587.

The cost of reducing starting RNA quantity for Illumina BeadArrays: A bead-level dilution experiment
Lynch AG;Hadfield J;Dunning MJ;Osborne M;Thorne NP;Tavare S
BMC Genomics 2010; 11 ():540.
PubMed;  DOI: 10.1186/1471-2164-11-540.

The importance of platform annotation in interpreting microarray data
Dunning MJ;Curtis C;Barbosa-Morais NL;Caldas C;Tavare S;Lynch AG
Lancet Oncol 2010; 11 (8):717-717.

SIK2 Is a Centrosome Kinase Required for Bipolar Mitotic Spindle Formation that Provides a Potential Target for Therapy in Ovarian Cancer
Ahmed AA;Lu Z;Jennings NB;Etemadmoghadam D;Capalbo L;Jacamo RO;Barbosa-Morais N;Le XF;Vivas-Mejia P;Lopez-Berestein G;Grandjean G;Bartholomeusz G;Liao W;Andreeff M;Bowtell D;Glover DM;Sood AK;Bast RC;Australian Ovarian Canc Study Grp
Cancer Cell 2010; 18 (2):109-121.
PubMed;  DOI: 10.1016/j.ccr.2010.06.018.

Data analysis issues for allele-specific expression using Illumina's GoldenGate assay
Ritchie ME;Forrest MS;Dimas AS;Daelemans C;Dermitzakis ET;Deloukas P;Tavare S
BMC Bioinformatics 2010; 11 ():280.
DOI: 10.1186/1471-2105-11-280.

The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans
Clark AM;Goldstein LD;Tevlin M;Tavare S;Shaham S;Miska EA
Nucleic Acids Res 2010; 38 (11):3780-3793.
UKPubMed (open access)PubMed;  DOI: 10.1093/nar/gkq083.

Does the Use of a Handheld Fan Improve Chronic Dyspnea? A Randomized, Controlled, Crossover Trial
Galbraith S;Fagan P;Perkins P;Lynch A;Booth S
J Pain Symptom Manage 2010; 39 (5):831-838.
PubMed;  DOI: 10.1016/j.jpainsymman.2009.09.024.

Identification and correction of previously unreported spatial phenomena using raw Illumina BeadArray data
Smith ML;Dunning MJ;Tavare S;Lynch AG
BMC Bioinformatics 2010; 11 ():208.
UKPubMed (open access)PubMed;  DOI: 10.1186/1471-2105-11-208.

High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta
Daelemans C;Ritchie ME;Smits G;Abu-Amero S;Sudbery IM;Forrest MS;Campino S;Clark TG;Stanier P;Kwiatkowski D;Deloukas P;Dermitzakis ET;Tavare S;Moore GE;Dunham I
BMC Genet 2010; 11 ():25.
DOI: 10.1186/1471-2156-11-25.

CNAnova: a new approach for finding recurrent copy number abnormalities in cancer SNP microarray data
Ivakhno S;Tavare S
Bioinformatics 2010; 26 (11):1395-1402.
PubMed;  DOI: 10.1093/bioinformatics/btq145.

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
Ahmed AA;Etemadmoghadam D;Temple J;Lynch AG;Riad M;Sharma R;Stewart C;Fereday S;Caldas C;DeFazio A;Bowtell D;Brenton JD;Australian Ovarian Canc Study Grp
J Pathol 2010; 221 (1):49-56.
PubMed;  DOI: 10.1002/path.2696.

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data
Barbosa-Morais NL;Dunning MJ;Samarajiwa SA;Darot JFJ;Ritchie ME;Lynch AG;Tavare S
Nucleic Acids Res 2010; 38 (3):e17.
UKPubMed (open access)PubMed;  DOI: 10.1093/nar/gkp942.

2009

Symptom classification in irritable bowel syndrome as a guide to treatment.
Wiesner M;Naylor SJ;Copping A;Furlong A;Lynch AG;Parkes M;Hunter JO
Scand J Gastroenterol 2009; 44 (7):796-803.
PubMed;  DOI: 10.1080/00365520902964705.

Swift: primary data analysis for the Illumina Solexa sequencing platform.
Whiteford N;Skelly T;Curtis C;Ritchie ME;Lohr A;Zaranek AW;Abnizova I;Brown C
Bioinformatics 2009; 25 (17):2194-2199.
UKPubMed (open access)PubMed;  DOI: 10.1093/bioinformatics/btp383.

The pitfalls of platform comparison: DNA copy number array technologies assessed
Curtis C;Lynch AG;Dunning MJ;Spiteri I;Marioni JC;Hadfield J;Chin SF;Brenton JD;Tavare S;Caldas C
BMC Genomics 2009; 10 ():588.
UKPubMed (open access)PubMed;  DOI: 10.1186/1471-2164-10-588.

Characterisation of microRNA expression in post-natal mouse mammary gland development
Avril-Sassen S;Goldstein LD;Stingl J;Blenkiron C;Le Quesne J;Spiteri I;Karagavriilidou K;Watson CJ;Tavare S;Miska EA;Caldas C
BMC Genomics 2009; 10 ():548.
UKPubMed (open access)PubMed;  DOI: 10.1186/1471-2164-10-548.

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression
Fernando H;Sewitz S;Darot J;Tavare S;Huppert JL;Balasubramanian S
Nucleic Acids Res 2009; 37 (20):6716-6722.
UKPubMed (open access)PubMed;  DOI: 10.1093/nar/gkp740.

BayesPeak: Bayesian analysis of ChIP-seq data
Spyrou C;Stark R;Lynch AG;Tavare S
BMC Bioinformatics 2009; 10 ():299.
UKPubMed (open access)PubMed;  DOI: 10.1186/1471-2105-10-299.

R/Bioconductor software for Illumina's Infinium whole-genome genotyping BeadChips
Ritchie ME;Carvalho BS;Hetrick KN;Tavare S;Irizarry RA
Bioinformatics 2009; 25 (19):2621-2623.
UKPubMed (open access)PubMed;  DOI: 10.1093/bioinformatics/btp470.

Product Length, Dye Choice, and Detection Chemistry in the Bead-Emulsion Amplification of Millions of Single DNA Molecules in Parallel
Tiemann-Boege I;Curtis C;Shinde DN;Goodman DB;Tavare S;Arnheim N
Anal Chem 2009; 81 (14):5770-5776.
UKPubMed (open access)PubMed;  DOI: 10.1021/ac900633y.

Isolation of Stool-Derived Mucus Provides a High Yield of Colonocytes Suitable for Early Detection of Colorectal Carcinoma
White V;Scarpini C;Barbosa-Morais NL;Ikelle E;Carter S;Laskey RA;Miller R;Coleman N
Cancer Epidemiol Biomarkers Prev 2009; 18 (7):2006-2013.
PubMed;  DOI: 10.1158/1055-9965.EPI-08-1145.

Many colorectal cancers are 'flat' clonal expansions
Siegmund KD;Marjoram P;Tavare S;Shibata D
Cell Cycle 2009; 8 (14):2187-2193.

Generation and validation of a revised classification for oesophageal and junctional adenocarcinoma.
Peters CJ;Hardwick RH;Vowler SL;Fitzgerald RC;Oesophageal Cancer Clinical and Molecular Stratification Study Group
Br J Surg 2009; 96 (7):724-733.
PubMed;  DOI: 10.1002/bjs.6584.

Autophagy mediates the mitotic senescence transition
Young ARJ;Narita M;Ferreira M;Kirschner K;Sadaie M;Darot JFJ;Tavare S;Arakawa S;Shimizu S;Watt FM;Narita M
Genes Dev 2009; 23 (7):798-803.
UKPubMed (open access)PubMed;  DOI: 10.1101/gad.519709.

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers
Siegmund KD;Marjoram P;Woo YJ;Tavare S;Shibata D
Proc Natl Acad Sci U S A 2009; 106 (12):4828-4833.
UKPubMed (open access)PubMed;  DOI: 10.1073/pnas.0810276106.

Association of ESR1 gene tagging SNPs with breast cancer risk
Dunning AM;Healey CS;Baynes C;Maia AT;Scollen S;Vega A;Rodriguez R;Barbosa-Morais NL;Ponder BAJ;Low YL;Bingham S;Haiman CA;Le Marchand L;Broeks A;Schmidt MK;Hopper J;Southey M;Beckmann MW;Fasching PA;Peto J;Johnson N;Bojesen SE;Nordestgaard B;Milne RL;Benitez J;Hamann U;Ko Y;Schmutzler RK;Burwinkel B;Schurmann P;Dork T;Heikkinen T;Nevanlinna H;Lindblom A;Margolin S;Mannermaa A;Kosma VM;Chen XQ;Spurdle A;Change-Claude J;Flesch-Janys D;Couch FJ;Olson JE;Severi G;Baglietto L;Brresen-Dale AL;Kristensen V;Hunter DJ;Hankinson SE;Devilee P;Vreeswijk M;Lissowska J;Brinton L;Liu JJ;Hall P;Kang D;Yoo KY;Shen CY;Yu JC;Anton-Culver H;Ziogoas A;Sigurdson A;Struewing J;Easton DF;Garcia-Closas M;Humphreys MK;Morrison J;Pharoah PDP;Pooley KA;Chenevix-Trench G;SEARCH;EPIC;MEC;ABCS;ABCFS;BBCC;BBCS;CGPS;CNIO-BCS;GENICA;GC-HBOC;HABCS;HEBCS;KARBAC;KBCS;kConFab;AOCS Management Grp;MARIE;MCBCS;MCCS;NBCS;NHS;ORIGO;PBCS;SASBAC;SEBCS;TWBCS;UCIBCS;USRTS;BCAC
Hum Mol Genet 2009; 18 (6):1131-1139.
UKPubMed (open access)PubMed;  DOI: 10.1093/hmg/ddn429.

Older individuals appear to acquire mitotically older colorectal cancers
Woo YJ;Siegmund KD;Tavare S;Shibata D
J Pathol 2009; 217 (4):483-488.
PubMed;  DOI: 10.1002/path.2506.

Population Genetic Inference From Resequencing Data
Jiang R;Tavare S;Marjoram P
Genetics 2009; 181 (1):187-197.

2008

Myocardial gene expression associated with genetic cardiac hypertrophy in the absence of hypertension
Dwyer JP;Ritchie ME;Smyth GK;Harrap SB;Delbridge LMD;Domenighetti AA;Di Nicolantonio R
Hypertens Res 2008; 31 (5):941-955.

Spike-in validation of an Illumina-specific variance-stabilizing transformation
Dunning MJ;Ritchie ME;Barbosa-Morais NL;Tavare S;Lynch AG
BMC Res Notes 2008; 1 ():1-18.
PubMed; 

Serum albumin level as a predictor of outcome in traumatic brain injury: Potential for treatment
Bernard F;Al-Tamimi YZ;Chafield D;Lynch AG;Matta BF;Menon DK
J Trauma 2008; 64 (4):872-875.

Suprarenal endograft fixation and medium-term renal function: Systematic review and meta-analysis
Walsh SR;Boyle JR;Lynch AG;Sadat U;Carpenter JP;Tang TY;Gaunt ME
J Vasc Surg 2008; 47 (6):1364-1370.
PubMed;  DOI: 10.1016/j.jvs.2007.11.029.

Integrative analysis of RUNX1 downstream pathways and target genes
Michaud J;Simpson KM;Escher R;Buchet-Poyau K;Beissbarth T;Carmichael C;Ritchie ME;Schutz F;Cannon P;Liu M;Shen X;Ito Y;Raskind WH;Horwitz MS;Osato M;Turner DR;Speed TP;Kavallaris M;Smyth GK;Scott HS
BMC Genomics 2008; 9 ():363.

Functional and metabolic remodelling in GLUT4-deficient hearts confers hyper-responsiveness to substrate intervention
Huggins CE;Domenighetti AA;Ritchie ME;Khalil N;Favaloro JM;Proletto J;Smyth GK;Pepe S;Delbridge LMD
J Mol Cell Cardiol 2008; 44 (2):270-280.

Tissue-specific splicing factor gene expression signatures
Grosso AR;Gomes AQ;Barbosa-Morais NL;Caldeira S;Thorne NP;Grech G;von Lindern M;Carmo-Fonseca M
Nucleic Acids Res 2008; 36 (15):4823-4832.

Assessing agreement between multiple raters with missing rating information, applied to breast cancer tumour grading.
Fanshawe TR;Lynch AG;Ellis IO;Green AR;Hanka R
PLoS ONE 2008; 3 ():e2925.
UKPubMed (open access)PubMed;  DOI: 10.1371/journal.pone.0002925.

BASH: a tool for managing BeadArray spatial artefacts
Cairns JM;Dunning MJ;Ritchie ME;Russell R;Lynch AG
Bioinformatics 2008; 24 (24):2921-2922.
UKPubMed (open access)PubMed;  DOI: 10.1093/bioinformatics/btn557.

Modifier Effects between Regulatory and Protein-Coding Variation
Dimas AS;Stranger BE;Beazley C;Finn RD;Ingle CE;Forrest MS;Ritchie ME;Deloukas P;Tavare S;Dermitzakis ET
PLoS Genet 2008; 4 (10):e1000244.

AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma
Veerakumarasivam A;Goldstein LD;Saeb-Parsy K;Scott HE;Warren A;Thorne NP;Mills IG;Venkitaraman A;Neal DE;Kelly JD
Cell Cycle 2008; 7 (22):3525-3533.

Species-specific transcription in mice carrying human chromosome 21
Wilson MD;Barbosa-Morais NL;Schmidt D;Conboy CM;Vanes L;Tybulewicz VLJ;Fisher EMC;Tavare S;Odom DT
Science 2008; 322 (5900):434-438.

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)
Rakyan VK;Down TA;Thorne NP;Flicek P;Kulesha E;Graf S;Tomazou EM;Backdahl L;Johnson N;Herberth M;Howe KL;Jackson DK;Miretti MM;Fiegler H;Marioni JC;Birney E;Hubbard TJP;Carter NP;Tavare S;Beck S
Genome Res 2008; 18 (9):1518-1529.
UKPubMed (open access)PubMed;  DOI: 10.1101/gr.077479.108.

Hidden copy number variation in the HapMap population
Marioni JC;White M;Tavare S;Lynch AG
Proc Natl Acad Sci U S A 2008; 105 (29):10067-10072.

PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes
Git A;Spiteri I;Blenkiron C;Dunning MJ;Pole JCM;Chin SF;Wang YZ;Smith J;Livesey FJ;Caldas C
Breast Cancer Res 2008; 10 (3):R54.
UKPubMed (open access)PubMed;  DOI: 10.1186/bcr2109.

Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline
Das PP;Bagijn MP;Goldstein LD;Woolford JR;Lehrbach NJ;Sapetschnig A;Buhecha HR;Gilchrist MJ;Howe KL;Stark R;Matthewss N;Berezilkov E;Ketting RF;Tavare S;Miska EA
Mol Cell 2008; 31 (1):79-90.
PubMed;  DOI: 10.1016/j.molcel.2008.06.003.

A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
Down TA;Rakyan VK;Turner DJ;Flicek P;Li H;Kulesha E;Graf S;Johnson N;Herrero J;Tomazou EM;Thorne NP;Backdahl L;Herberth M;Howe KL;Jackson DK;Miretti MM;Marioni JC;Birney E;Hubbard TJP;Durbin R;Tavare S;Beck S
Nat Biotechnol 2008; 26 (7):779-785.
UKPubMed (open access)PubMed;  DOI: 10.1038/nbt1414.

Pediatric malignant germ cell tumors show characteristic transcriptome profiles
Palmer RD;Barbosa-Morais NL;Gooding EL;Muralidhar B;Thornton CM;Pett MR;Roberts I;Schneider DT;Thorne N;Tavare S;Nicholson JC;Coleman N;Children's Canc & Leukaemia Grp
Cancer Res 2008; 68 (11):4239-4247.
PubMed;  DOI: 10.1158/0008-5472.CAN-07-5560.

Inferring relative numbers of human leucocyte genome replications
Chu M;Siegmund KD;Hao QL;Crooks GM;Tavare S;Shibata D
Br J Haematol 2008; 141 (6):862-871.
PubMed;  DOI: 10.1111/j.1365-2141.2008.07142.x.

Statistical issues in the analysis of Illumina data
Dunning MJ;Barbosa-Morais NL;Lynch AG;Tavare S;Ritchie ME
BMC Bioinformatics 2008; 9 ():85.

Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population
Driver KE;Song H;Lesueur F;Ahmed S;Barbosa-Morais NL;Tyrer JP;Ponder BAJ;Easton DF;Pharoah PDP;Dunning AM;SEARCH Team
Carcinogenesis 2008; 29 (2):333-341.
UKPubMed (open access)PubMed;  DOI: 10.1093/carcin/bgm284.

2007

Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor.
Conboy CM;Spyrou C;Thorne NP;Wade EJ;Barbosa-Morais NL;Wilson MD;Bhattacharjee A;Young RA;Tavare S;Lees JA;Odom DT
PLoS ONE 2007; 2 (10):e1061.

Breaking the waves: improved detection of copy number variation from microarray-based comparative genomic hybridization
Marioni JC;Thorne NP;Valsesia A;Fitzgerald T;Redon R;Fiegler H;Andrews TD;Stranger BE;Lynch AG;Dermitzakis ET;Carter NP;Tavare S;Hurles ME
Genome Biol 2007; 8 (10):R228.

High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
Chin SF;Teschendorff AE;Marioni JC;Wang Y;Barbosa-Morais NL;Thorne NP;Costa JL;Pinder SE;De Wiel MAV;Green AR;Ellis IO;Porter PL;Tavare S;Brenton JD;Ylstra B;Caldas C
Genome Biol 2007; 8 (10):R215.

MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
Blenkiron C;Goldstein LD;Thorne NP;Spiteri I;Chin SF;Dunning MJ;Barbosa-Morais NL;Teschendorff AE;Green AR;Ellis IO;Tavare S;Caldas C;Miska EA
Genome Biol 2007; 8 (10):R214.

High grade glioma: Imaging combined with pathological grade defines management and predicts prognosis
Burnet NG;Lynch AG;Jefferies SJ;Price SJ;Jones PH;Antoun NM;Xuereb JH;Pohl U
Radiother Oncol 2007; 85 (3):371-378.

Early radiotherapy dose response and lack of hypersensitivity effect in normal brain tissue: a sequential dynamic susceptibility imaging study of cerebral perfusion
Price SJ;Jena R;Green HAL;Kirkby NF;Lynch AG;Coles CE;Pickard JD;Giltard JH;Burnet NG
Clin Oncol (R Coll Radiol) 2007; 19 (8):577-587.

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor
Massie CE;Adryan B;Barbosa-Morais NL;Lynch AG;Tran MG;Neal DE;Mills IG
EMBO Rep 2007; 8 (9):871-878.

Population genomics of human gene expression
Stranger BE;Nica AC;Forrest MS;Dimas A;Bird CP;Beazley C;Ingle CE;Dunning M;Flicek P;Koller D;Montgomery S;Tavare S;Deloukas P;Dermitzakis ET
Nat Genet 2007; 39 (10):1217-1224.

beadarray: R classes and methods for Illumina bead-based data
Dunning MJ;Smith ML;Ritchie ME;Tavare S
Bioinformatics 2007; 23 (16):2183-2184.

Global microRNA profiles in cervical squamous cell carcinoma depend on Drosha expression levels
Muralidhar B;Goldstein LD;Ng G;Winder DM;Palmer RD;Gooding EL;Barbosa-Morais NL;Mukherjee G;Thorne NP;Roberts I;Pett MR;Coleman N
J Pathol 2007; 212 (4):368-377.

Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging
Chu MW;Siegmund KD;Eckstam CL;Kim JY;Yang AS;Kanel GC;Tavare S;Shibata D
BMC Med Genet 2007; 8 ():50.

Stem cell chronicles: Autobiographies within Genomes
Shibata D;Tavare S
Stem Cell Rev 2007; 3 (1):94-103.

Numbers of copy-number variations and false-negative rates will be underestimated if we do not account for the dependence between repeated experiments
Lynch AG;Marioni JC;Tavare S
Am J Hum Genet 2007; 81 (2):418-420.

The stem cell population of the human colon crypt: Analysis via methylation patterns
Nicolas P;Kim KM;Shibata D;Tavare S
PLoS Comput Biol 2007; 3 (3):364-374.

Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers
Chin SF;Wang Y;Thorne NP;Teschendorff AE;Pinder SE;Vias M;Naderi A;Roberts I;Barbosa-Morais NL;Garcia MJ;Iyer NG;Kranjac T;Robertson JFR;Aparicio S;Tavare S;Ellis I;Brenton JD;Caldas C
Oncogene 2007; 26 (13):1959-1970.

A gene-expression signature to predict survival in breast cancer across independent data sets
Naderi A;Teschendorff AE;Barbosa-Morais NI;Pinder SE;Green AR;Powe DG;Robertson JFR;Aparicio S;Ellis IO;Brenton JD;Caldas C
Oncogene 2007; 26 (10):1507-1516.

Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
Lynch AG;Neal DE;Kelly JD;Burtt GJ;Thorne NP
BMC Bioinformatics 2007; 8 ():26.

Relative impact of nucleotide and copy number variation on gene expression phenotypes
Stranger BE;Forrest MS;Dunning M;Ingle CE;Beazley C;Thorne N;Redon R;Bird CP;de Grassi A;Lee C;Tyler-Smith C;Carter N;Scherer SW;Tavare S;Deloukas P;Hurles ME;Dermitzakis ET
Science 2007; 315 (5813):848-853.

2006

MMASS: an optimized array-based method for assessing CpG island methylation
Ibrahim AEK;Thorne NP;Baird K;Barbosa-Morais NL;Tavare S;Collins VP;Wyllie AH;Arends MJ;Brenton JD
Nucleic Acids Res 2006; 34 (20):e136.

Counting divisions in a human somatic cell tree - How, what and why?
Shibata D;Tavare S
Cell Cycle 2006; 5 (6):610-614.

BioHMM: a heterogeneous hidden Markov model for segmenting array CGH data
Marioni JC;Thorne NP;Tavare S
Bioinformatics 2006; 22 (9):1144-1146.

Human hair genealogies and stem cell latency
Kim JY;Tavare S;Shibata D
BMC Biol 2006; 4 ():2.

2005

Age-related human small intestine methylation: evidence for stem cell niches
Kim JY;Siegmund KD;Tavare S;Shibata D
BMC Med 2005; 3 ():10.

Genome-wide associations of gene expression variation in humans
Stranger BE;Forrest MS;Clark AG;Minichiello MJ;Deutsch S;Lyle R;Hunt S;Kahl B;Antonarakis SE;Tavare S;Deloukas P;Dermitzakis ET
PLoS Genet 2005; 1 (6):695-704.

Counting human somatic cell replications: Methylation mirrors endometrial stem cell divisions
Kim JY;Tavare S;Shibata D
Proc Natl Acad Sci U S A 2005; 102 (49):17739-17744.