David Tuveson publications

CRI researcher David Tuveson profile image

Cambridge Research Institute
Robinson Way
Cambridge
CB2 0RE
United Kingdom

Tel: 01223 404190

Primary research papers

The following publications have been supported by Cancer Research UK funding for this researcher.

2011

Stromal biology and therapy in pancreatic cancer
Neesse A;Michl P;Frese KK;Feig C;Cook N;Jacobetz MA;Lolkema MP;Buchholz M;Olive KP;Gress TM;Tuveson DA
Gut 2011; 60 (6 ):861-868.
PubMed;  DOI: 10.1136/gut.2010.226092.

2010

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-alpha
Kraman M;Bambrough PJ;Arnold JN;Roberts EW;Magiera L;Jones JO;Gopinathan A;Tuveson DA;Fearon DT
Science 2010; 330 (6005):827-830.
PubMed;  DOI: 10.1126/science.1195300.

2009

C-Raf Inhibits MAPK Activation and Transformation by B-Raf(V600E)
Karreth FA;DeNicola GM;Winter SP;Tuveson DA
Mol Cell 2009; 36 (3):477-486.
PubMed;  DOI: 10.1016/j.molcel.2009.10.017.

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Olive KP;Jacobetz MA;Davidson CJ;Gopinathan A;McIntyre D;Honess D;Madhu B;Goldgraben MA;Caldwell ME;Allard D;Frese KK;DeNicola G;Feig C;Combs C;Winter SP;Ireland-Zecchini H;Reichelt S;Howat WJ;Chang A;Dhara M;Wang LF;Ruckert F;Grutzmann R;Pilarsky C;Izeradjene K;Hingorani SR;Huang P;Davies SE;Plunkett W;Egorin M;Hruban RH;Whitebread N;McGovern K;Adams J;Iacobuzio-Donahue C;Griffiths J;Tuveson DA
Science 2009; 324 (5933):1457-1461.
PubMed; 

An shRNA Silencing a Non-Toxic Transgene Reduces Nutrient Consumption and Increases Production of Adenoviral Vectors in a Novel Packaging Cell
Wang LF;Qi XG;Shen RZ;Sun Y;Tuveson DA
J Cell Physiol 2009; 219 (2):365-371.

2008

The use of GEM models for experimental cancer therapeutics
Gopinathan A;Tuveson DA
Dis Model Mech 2008; 1 (2-3):83-86.
PubMed; 

A phase I trial of the oral, multikinase inhibitor sorafenib in combination with carboplatin and paclitaxel
Flaherty KT;Schiller J;Schuchter LM;Liu G;Tuveson DA;Redlinger M;Lathia C;Xia C;Petrenciuc O;Hingorani SR;Jacobetz MA;Van Belle PA;Elder D;Brose MS;Weber BL;Albertini MR;O'Dwyer PJ
Clin Cancer Res 2008; 14 (15):4836-4842.

K-Ras-driven pancreatic cancer mouse model for anticancer inhibitor analyses
Cook N;Olive KR;Frese K;Tuveson DA
Methods Enzymol 2008; 439 ():73-85.

2007

Maximizing mouse cancer models
Frese KK;Tuveson DA
Nat Rev Cancer 2007; 7 (9):645-658.