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Cancer Research UK Cambridge Institute

 

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Established in early 2017, the Halim group focuses on interactions between the immune system and cancers.

The immune system plays a critical role in many different aspects of cancer. Some immune cells are efficient at detecting and killing tumour cells, while in other instances inflammation is the underlying cause of cancer. Our lab is focused on a newly discovered group of immune cells, called innate lymphoid cells (ILC).  Importantly, we have discovered that ILC have potent immune-regulatory properties that may be critical in tumourigenesis.

We use in vivo and in vitro models and techniques to investigate the fundamental mechanisms that regulate “good” versus “bad” inflammation in cancer.  This understanding is critical for both treatment and prevention.